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- The notochord is a key evolutionary structure in chordates1. It originated more than 560 million years ago from a common ancestor shared with nonchordate deuterostomes1. In vertebrates, the notochord develops during gastrulation from cells that migrate anteriorly in the midline between the hypoblast and the epiblast2. It later becomes part of the vertebral column2. There are two main hypotheses for the origin of the notochord: the de novo theory and the axochord theory3.Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.They probably originated more than 560 million years ago from a common ancestor shared with nonchordate deuterostomes (echinoderms and hemichordates), and the occurrence of a novel fishlike (tadpole-type) larva was a key evolutionary event leading to the evolution of chordates.neupsykey.com/evolutionary-origin-of-the-notochord/In later vertebrate development, it becomes part of the vertebral column. The notochord derives during gastrulation (infolding of the blastula, or early embryo) from cells that migrate anteriorly in the midline between the hypoblast and the epiblast (inner and outer layers of the blastula).www.britannica.com/science/notochordTwo main hypotheses for the origin of the notochord were proposed, the de novo theory and the axochord theory. The former states that notochord has developed de novo from the mid-dorsal archenteron of a chordate ancestor with simple morphology and no central nervous system nor notochord homolog.www.mdpi.com/1424-2818/13/10/462
The development of the human notochord - PMC
The development of the human notochord has three distinct phases, leading to the definitive notochord, also dubbed the notochord proper or notochord senso stricto. This structure develops in three phases between Carnegie stage 8 …
Notochord - Wikipedia
Did the notochord evolve from an ancient axial muscle? The …
(PDF) Evolution of the notochord - ResearchGate
Oct 5, 2015 · The transition from notochord to vertebral column is a crucial milestone in chordate evolution and in prenatal development of all vertebrates.
Development of the annelid axochord: Insights into …
Sep 12, 2014 · We identify a population of mesodermal cells in a developing invertebrate, the marine annelid Platynereis dumerilii, that converges and extends toward the midline and expresses a notochord-specific combination of genes.
Evolution of the notochord - PubMed
Origin of the Chordate Notochord - MDPI
Sep 25, 2021 · During the late 20th century, the development of molecular and genetic tools in biology brought about a revival of studies on the evolutionary path of notochord development. Two main hypotheses for the origin of the …
Development and involution of the notochord in the human spine.
Animal Evolution: Stiff or Squishy Notochord Origins?
Dec 1, 2014 · The notochord is considered an evolutionary novelty and one of the defining characters of chordates. A new study of an annelid challenges this view and proposes an earlier evolutionary origin in the most recent common …
The Notochord | Development, Evolution and contributions to the …
How was the notochord born? - PubMed
Animal Evolution: Stiff or Squishy Notochord Origins?
Development of the annelid axochord: insights into notochord …
Evolution of the notochord - PMC - National Center for …
How was the notochord born? - Satoh - 2012 - Evolution & ...
(PDF) Origin of the Chordate Notochord - ResearchGate
How was the notochord born? - Satoh - 2012 - Evolution & ...
Scientists Have Grown a Human Spine In a Lab - Popular …